DLG4 antibody (Middle Region)

Catalog No. ABIN2784457

This anti-DLG4 antibody is a Rabbit Polyclonal antibody detecting DLG4 in WB. Suitable for Rat, Human, Mouse, Cow, Rabbit, Zebrafish (Danio rerio), Dog, Horse and Guinea Pig.

Quick Overview for DLG4 antibody (Middle Region) (ABIN2784457)

Target: DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))

Reactivity: Rat, Human, Mouse, Cow, Rabbit, Zebrafish (Danio rerio), Dog, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DLG4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DLG4 Antibody

Binding Specificity: Middle Region

Sequence: AAHLHPIAIF IRPRSLENVL EINKRITEEQ ARKAFDRATK LEQEFTECFS

Predicted Reactivity: Cow: 100%, Dog: 79%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against DLG4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DLG4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 767 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DLG4

Target: DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))

Alternative Name: DLG4

Background: This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: PSD95, SAP90, SAP-90
Protein Interaction Partner: SPRR2A, UBC, BAI1, Mbp, MED28, RAD23A, MDM2, PCDH10, MAP1A, KCNA3, KCNA4, GRIN2B, GRIK2, ADRB1, CUL3, KCNA5, GRIN2A, ERBB4, KHDRBS1, ELAVL1, LRFN1, TANC1, GRASP, DLGAP4, SYNGAP1, GRIN1, LPHN1, ARHGAP32, GNG13, SIPA1L1, ASIC3, NDOR1, SEMA4G, SEMA4B, LIN7B,
Protein Size: 767

Molecular Weight: 85 kDa

Gene ID: 1742

NCBI Accession: NM_001365, NP_001356

UniProt: P78352

Pathways: Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development, Asymmetric Protein Localization, Regulation of long-term Neuronal Synaptic Plasticity