WASF2 antibody (Middle Region)

Catalog No. ABIN2784517

The Rabbit Polyclonal anti-WASF2 antibody (ABIN2784517) specifically detects WASF2 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit samples.

Quick Overview for WASF2 antibody (Middle Region) (ABIN2784517)

Target: WASF2 (WAS Protein Family, Member 2 (WASF2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WASF2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-WASF2 Antibody

Binding Specificity: Middle Region

Purpose: Wasf2 Antibody - middle region

Sequence: QNGSIGSVEN VDAASYPPPP QSDSASSPSP SFSEDNLPPP PAEFSYPADN

Predicted Reactivity: Cow: 86%, Dog: 79%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 85%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against Wasf2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51324-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for WASF2

Target: WASF2 (WAS Protein Family, Member 2 (WASF2))

Alternative Name: Wasf2

Background:

Background Information: Wasf2 is a downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. It promotes formation of actin filaments. Wasf2 is a part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.

Gene Name: WAS protein family, member 2

Alternative Symbols: WAV, WAVE2, AW742646, D4Ertd13, D4Ertd13e

Molecular Weight: 55kDa

Gene ID: 242687

NCBI Accession: NP_700472

UniProt: Q8BH43

Pathways: RTK Signaling