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INTS4 antibody (Middle Region)

INTS4 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2784574
$472.77
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  • Target See all INTS4 Antibodies
    INTS4 (Integrator Complex Subunit 4 (INTS4))
    Binding Specificity
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 16
    • 14
    • 14
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)
    Host
    • 16
    Rabbit
    Clonality
    • 16
    Polyclonal
    Conjugate
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This INTS4 antibody is un-conjugated
    Application
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    PAEVVKILQT MLRQSAFLHL PLPEQIHKAS ATIIEPAGES DNPLRFTSGL
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
    Characteristics
    This is a rabbit polyclonal antibody against INTS4. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human INTS4
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 963 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    INTS4 (Integrator Complex Subunit 4 (INTS4))
    Alternative Name
    INTS4 (INTS4 Products)
    Synonyms
    DDBDRAFT_0187061 antibody, DDBDRAFT_0234080 antibody, DDB_0187061 antibody, DDB_0234080 antibody, INT4 antibody, MST093 antibody, 2610034N24Rik antibody, AA692684 antibody, AW493223 antibody, RGD1305036 antibody, integrator complex subunit 4 antibody, HEAT repeat-containing protein antibody, ARM repeat superfamily protein antibody, integrator complex subunit 4 L homeolog antibody, CpipJ_CPIJ015422 antibody, ints4 antibody, NAEGRDRAFT_79682 antibody, INTS4 antibody, SIEL antibody, Ints4 antibody, ints4.L antibody
    Background
    INTS4 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1) and U2 (RNU2).INTS4 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A, MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1, MIM 180680) and U2 (RNU2, MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM].
    Alias Symbols: INT4, MGC16733, MST093
    Protein Interaction Partner: USHBP1, ZMIZ2, HGS, UBC, HECW2, INTS9, UBD, SUMO2, INTS10, SHFM1, INTS5, INTS3, INTS6, INTS1, RPAP2, KIAA0513,
    Protein Size: 963
    Molecular Weight
    108 kDa
    Gene ID
    92105
    NCBI Accession
    NM_033547, NP_291025
    UniProt
    Q96HW7
    Pathways
    SARS-CoV-2 Protein Interactome
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