ADH5 antibody (Middle Region)

Catalog No. ABIN2784616

The Rabbit Polyclonal anti-ADH5 antibody is suitable to detect ADH5 in samples from Human, Mouse, Rat, Pig, Horse and Rabbit. It has been validated for WB.

Quick Overview for ADH5 antibody (Middle Region) (ABIN2784616)

Target: ADH5 (Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5))

Reactivity: Human, Mouse, Rat, Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADH5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ADH5 Antibody

Binding Specificity: Middle Region

Sequence: KSVESVPKLV SEYMSKKIKV DEFVTHNLSF DEINKAFELM HSGKSIRTVV

Predicted Reactivity: Horse: 79%, Human: 100%, Mouse: 93%, Pig: 79%, Rabbit: 83%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against ADH5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ADH5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 374 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ADH5

Target: ADH5 (Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5))

Alternative Name: ADH5

Background: This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene.
Alias Symbols: ADH-3, ADHX, FDH, FALDH, GSNOR, GSH-FDH
Protein Interaction Partner: UBC, HDAC1, SNTA1, ADH5, PQLC1, VTN, PRDX1, ESRRA, CSNK2B, ARNT, APP, TP63, TP73, TP53, CHD3,
Protein Size: 374

Molecular Weight: 40 kDa

Gene ID: 128

NCBI Accession: NM_000671, NP_000662

UniProt: P11766