ASB11 antibody (C-Term)

Catalog No. ABIN2784642

The Rabbit Polyclonal anti-ASB11 antibody is suitable to detect ASB11 in samples from Human, Mouse, Rat, Horse and Guinea Pig. It has been validated for WB.

Quick Overview for ASB11 antibody (C-Term) (ABIN2784642)

Target: ASB11 (Ankyrin Repeat and SOCS Box-Containing 11 (ASB11))

Reactivity: Human, Mouse, Rat, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASB11 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ASB11 Antibody

Binding Specificity: C-Term

Purpose: ASB11 Antibody - C-terminal region

Sequence: GQWLDTPLHA AARQSNVEVI HLLTDYGANL KRRNAQGKSA LDLAAPKSSV

Predicted Reactivity: Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against ASB11. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ASB11

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8094649

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ASB11

Target: ASB11 (Ankyrin Repeat and SOCS Box-Containing 11 (ASB11))

Alternative Name: ASB11

Background:

Background Information: ASB11 is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation.The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: Ankyrin repeat and SOCS box containing 11

Alternative Symbols: DKFZp779E2460, MGC119168, MGC119169

Protein Name: Ankyrin repeat and SOCS box protein 11

Molecular Weight: 33kDa

Gene ID: 140456

NCBI Accession: NP_001012428

UniProt: Q8WXH4