CHI3L1 antibody (Middle Region)

Catalog No. ABIN311477

There is 1 publication for this product available. The Rabbit Polyclonal anti-CHI3L1 antibody is suitable to detect CHI3L1 in samples from Human, Rat, Rabbit, Cow, Dog, Goat and Pig. It has been validated for WB and IF.

Quick Overview for CHI3L1 antibody (Middle Region) (ABIN311477)

Target: CHI3L1 (Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1))

Reactivity: Human, Rat, Rabbit, Cow, Dog, Goat, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHI3L1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-CHI3L1 Antibody

Binding Specificity: Middle Region

Purpose: CHI3L1 Antibody - middle region

Sequence: LDFISIMTYD FHGAWRGTTG HHSPLFRGQE DASPDRFSNT DYAVGYMLRL

Predicted Reactivity: Cow: 92%, Dog: 77%, Goat: 92%, Human: 100%, Pig: 92%, Rabbit: 100%, Rat: 77%

Characteristics: This is a rabbit polyclonal antibody against CHI3L1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CHI3L1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8096891

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-CHI3L1 antibody (ABIN311477)

Kao, Peng, Tsou, Salter, Lee: "Nerve growth factor promotes expression of novel genes in intervertebral disc cells that regulate tissue degradation." in: Journal of neurosurgery. Spine, pp. 1-9, (2014) (PubMed).

Target Details for CHI3L1

Target: CHI3L1 (Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1))

Alternative Name: CHI3L1

Background:

Background Information: CHI3L1 may play an important role in the capacity of cells to respond to and cope with changes in their environment. CHI3L1 may play a role in tissue remodeling and defense against pathogens. It belongs to the glycosyl hydrolase 18 family. CHI3L1 may play an important role in the capacity of cells to respond to and cope with changes in their environment.

Gene Name: Chitinase 3-like 1 (cartilage glycoprotein-39)

Alternative Symbols: GP39, ASRT7, GP-39, YK-40, YKL40, CGP-39, YKL-40, YYL-40, HC-gp39, HCGP-3P, hCGP-39

Protein Name: Chitinase-3-like protein 1

Molecular Weight: 43 kDa

Gene ID: 1116

NCBI Accession: NP_001267

UniProt: P36222