CRYM antibody (Middle Region)

Catalog No. ABIN2784722

The Rabbit Polyclonal anti-CRYM antibody has been validated for WB. It is suitable to detect CRYM in samples from Human, Mouse, Rat, Cow, Dog, Goat, Horse, Rabbit and Guinea Pig.

Quick Overview for CRYM antibody (Middle Region) (ABIN2784722)

Target: CRYM (Crystallin, mu (CRYM))

Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRYM antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CRYM Antibody

Binding Specificity: Middle Region

Sequence: AHINAVGASR PDWRELDDEL MKEAVLYVDS QEAALKESGD VLLSGAEIFA

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against CRYM. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CRYM

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 272 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CRYM

Target: CRYM (Crystallin, mu (CRYM))

Alternative Name: CRYM

Background: Crystallins are separated into two classes: taxon-specific and ubiquitous. The former class is also called phylogenetically-restricted crystallins. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. This gene encodes a taxon-specific crystallin protein that binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not perform a structural role in lens tissue, and instead it binds thyroid hormone for possible regulatory or developmental roles. Mutations in this gene have been associated with autosomal dominant non-syndromic deafness. Multiple alternatively spliced transcript variants have been found for this gene.
Alias Symbols: DFNA40, THBP
Protein Interaction Partner: TERF1, C7orf25, CDC37,
Protein Size: 272

Molecular Weight: 30 kDa

Gene ID: 1428

NCBI Accession: NM_001014444, NP_001014444

UniProt: D5MNX0

Pathways: Hormone Transport, Sensory Perception of Sound