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CLK2 antibody (N-Term)
CLK2
Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-CLK2 Antibody
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Target
See all CLK2 Antibodies
CLK2
(CDC-Like Kinase 2 (CLK2))
Binding Specificity
All epitopes for CLK2 antibodies
N-Term
Reactivity
All reactivities for CLK2 antibodies
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)
Host
All hosts for CLK2 antibodies
Rabbit
Clonality
All clonalities for CLK2 antibodies
Polyclonal
Conjugate
All conjugates for CLK2 antibodies
This CLK2 antibody is un-conjugated
Application
All applications for CLK2 antibodies
Western Blotting (WB)
Sequence
KFLHDNKLTH TDLKPENILF VNSDYELTYN LEKKRDERSV KSTAVRVVDF
Predicted Reactivity
Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
Characteristics
This is a rabbit polyclonal antibody against CLK2. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of human CLK2
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Alternatives
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Application Details
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Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for CLK2
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Target
CLK2
(CDC-Like Kinase 2 (CLK2))
Alternative Name
CLK2 (CLK2 Products )
Synonyms
MGC53993 antibody, hclk2 antibody, clk2 antibody, fb20c02 antibody, si:ch211-81a5.7 antibody, wu:fb20c02 antibody, MGC131228 antibody, hCLK2 antibody, AU041688 antibody, Tu52 antibody, CDC like kinase 2 antibody, CDC like kinase 2 S homeolog antibody, CDC-like kinase 2a antibody, CDC like kinase 2 L homeolog antibody, CDC-like kinase 2 antibody, CLK2 antibody, clk2.S antibody, clk2 antibody, clk2a antibody, clk2.L antibody, Clk2 antibody
Background
This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex, thereby influencing alternative transcript splicing. Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29 kDa)) gene on chromosome 19, resulting in the production of a fusion protein. Note that this gene is distinct from the TELO2 gene (GeneID:9894), which shares the CLK2 alias, but encodes a protein that is involved in telomere length regulation. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants. Protein Size: 271
Molecular Weight
29 kDa
Gene ID
1196
NCBI Accession
NM_001294339 , NP_001281268
UniProt
B7Z8N6
Pathways
Regulation of Carbohydrate Metabolic Process
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