ACTR3 antibody (N-Term)

Catalog No. ABIN2784770

The Rabbit Polyclonal anti-ACTR3 antibody (ABIN2784770) specifically detects ACTR3 in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Rabbit, Zebrafish (Danio rerio), Guinea Pig and Horse samples.

Quick Overview for ACTR3 antibody (N-Term) (ABIN2784770)

Target: ACTR3 (ARP3 Actin-Related Protein 3 (ACTR3))

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Zebrafish (Danio rerio), Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACTR3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ACTR3 Antibody

Binding Specificity: N-Term

Purpose: ACTR3 Antibody - N-terminal region

Sequence: IAIKESAKVG DQAQRRVMKG VDDLDFFIGD EAIEKPTYAT KWPIRHGIVE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against ACTR3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ACTR3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52094-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ACTR3

Target: ACTR3 (ARP3 Actin-Related Protein 3 (ACTR3))

Alternative Name: ACTR3

Background:

Background Information: The specific function of this gene has not yet been determined, however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Three transcript variants encoding two different isoforms have been found for this gene.

Gene Name: ARP3 actin related protein 3 homolog

Alternative Symbols: ARP3

Protein Name: actin-related protein 3

Molecular Weight: 47kDa

Gene ID: 10096

NCBI Accession: NP_005712

UniProt: P61158

Pathways: RTK Signaling, Regulation of Actin Filament Polymerization