SEC23IP antibody (N-Term)

Catalog No. ABIN2784867

The Rabbit Polyclonal anti-SEC23IP antibody (ABIN2784867) specifically detects SEC23IP in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig, Rabbit and Pig samples.

Quick Overview for SEC23IP antibody (N-Term) (ABIN2784867)

Target: SEC23IP (SEC23 Interacting Protein (SEC23IP))

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEC23IP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SEC23IP Antibody

Binding Specificity: N-Term

Purpose: SEC23IP Antibody - N-terminal region

Sequence: SIHTSAPQTF SYFSQVSSSS DPFGNIGQSP LTTAATSVGQ SGFPKPLTAL

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 88%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SEC23IP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SEC23IP

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52296-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SEC23IP

Target: SEC23IP (SEC23 Interacting Protein (SEC23IP))

Alternative Name: SEC23IP

Background:

Background Information: COPII-coated vesicles are involved in protein transport from the endoplasmic reticulum to the Golgi apparatus. The protein encoded by this gene was identified by its interaction with a mouse protein similar to yeast Sec23p, an essential component of the COPII. This protein shares significant similarity with phospholipid-modifying proteins, especially phosphatidic acid preferring-phospholipase A1. Overexpression of this protein has been shown to cause disorganization of the endoplasmic reticulum-Golgi intermediate compartment and Golgi apparatus, which suggests its role in the early secretory pathway.

Gene Name: SEC23 interacting protein

Alternative Symbols: P125, P125A, MSTP053, iPLA1beta

Protein Name: SEC23-interacting protein

Molecular Weight: 111kDa

Gene ID: 11196

NCBI Accession: NP_009121

UniProt: Q9Y6Y8