SPON2 antibody (Middle Region)

Catalog No. ABIN2784890

This Rabbit Polyclonal antibody specifically detects SPON2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio) and Dog.

Quick Overview for SPON2 antibody (Middle Region) (ABIN2784890)

Target: SPON2 (Spondin 2 (SPON2))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio), Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPON2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SPON2 Antibody

Binding Specificity: Middle Region

Sequence: GTDSGFTFSS PNFATIPQDT VTEITSSSPS HPANSFYYPR LKALPPIARV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against SPON2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SPON2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 331 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SPON2

Target: SPON2 (Spondin 2 (SPON2))

Alternative Name: SPON2

Background: SPON2 is a cell adhesion protein that promote adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. It is essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens.
Alias Symbols: DIL-1, DIL1, M-spondin, Mindin, MINDIN, M-SPONDIN
Protein Interaction Partner: UBC, KRT31,
Protein Size: 331

Molecular Weight: 36 kDa

Gene ID: 10417

NCBI Accession: NM_012445, NP_036577

UniProt: Q9BUD6