DAB1 antibody (Middle Region)

Catalog No. ABIN2784908

The Rabbit Polyclonal anti-DAB1 antibody (ABIN2784908) specifically detects DAB1 in WB. The antibody is reactive with Human, Mouse, Rat, Pig, Cow, Dog, Horse, Rabbit and Guinea Pig samples.

Quick Overview for DAB1 antibody (Middle Region) (ABIN2784908)

Target: DAB1 (Disabled Homolog 1 (Drosophila) (DAB1))

Reactivity: Human, Mouse, Rat, Pig, Cow, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAB1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DAB1 Antibody

Binding Specificity: Middle Region

Purpose: DAB1 Antibody - middle region

Sequence: PTTDDIFEEG FESPSKSEEQ EAPDGSQASS NSDPFGEPSG EPSGDNISPQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 79%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against DAB1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DAB1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52396-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for DAB1

Target: DAB1 (Disabled Homolog 1 (Drosophila) (DAB1))

Alternative Name: DAB1

Background:

Background Information: The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.

Gene Name: Disabled homolog 1 (Drosophila)

Alternative Symbols: SCA37

Protein Name: Disabled homolog 1

Molecular Weight: 60kDa

Gene ID: 1600

NCBI Accession: NP_066566

UniProt: O75553