Dynein Assembly Factor 4, Axonemal (DNAAF4) (C-Term) antibody

Catalog No. ABIN2784979

This Rabbit Polyclonal antibody specifically detects Dynein Assembly Factor 4, Axonemal in WB. It exhibits reactivity toward Human, Mouse, Rat, Zebrafish (Danio rerio), Rabbit, Horse, Guinea Pig, Dog and Cow.

Quick Overview for Dynein Assembly Factor 4, Axonemal (DNAAF4) (C-Term) antibody (ABIN2784979)

Target: Dynein Assembly Factor 4, Axonemal (DNAAF4)

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Rabbit, Horse, Guinea Pig, Dog, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Product Details

Binding Specificity: C-Term

Purpose: DNAAF4 Antibody - C-terminal region

Sequence: FATENYLAAI NAYNLAIRLN NKMPLLYLNR AACHLKLKNL HKAIEDSSKA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against DYX1C1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human DYX1C1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52547-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details

Target: Dynein Assembly Factor 4, Axonemal (DNAAF4)

Alternative Name: DNAAF4

Background:

Background Information: This gene encodes a tetratricopeptide repeat domain-containing protein. The encoded protein interacts with estrogen receptors and the heat shock proteins, Hsp70 and Hsp90. An homologous protein in rat has been shown to function in neuronal migration in the developing neocortex. A chromosomal translocation involving this gene is associated with a susceptibility to developmental dyslexia. Mutations in this gene are associated with deficits in reading and spelling. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream cell cycle progression 1 (CCPG1) gene.

Gene Name: dynein axonemal assembly factor 4

Alternative Symbols: RD, DYX1, EKN1, DYXC1, CILD25, DYX1C1

Protein Name: dynein assembly factor 4, axonemal

Molecular Weight: 48kDa

Gene ID: 161582

NCBI Accession: NP_570722

UniProt: Q8WXU2