Dynein Assembly Factor 4, Axonemal (DNAAF4) (Middle Region) antibody

Catalog No. ABIN2784980

The Rabbit Polyclonal anti-Dynein Assembly Factor 4, Axonemal antibody (ABIN2784980) specifically detects Dynein Assembly Factor 4, Axonemal in WB. The antibody is reactive with Human, Mouse, Rat, Zebrafish (Danio rerio), Saccharomyces cerevisiae, Rabbit, Horse, Guinea Pig, Dog and Cow samples.

Quick Overview for Dynein Assembly Factor 4, Axonemal (DNAAF4) (Middle Region) antibody (ABIN2784980)

Target: Dynein Assembly Factor 4, Axonemal (DNAAF4)

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Saccharomyces cerevisiae, Rabbit, Horse, Guinea Pig, Dog, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Product Details

Binding Specificity: Middle Region

Purpose: DNAAF4 Antibody - middle region

Sequence: TDNANARMKA HVRRGTAFCQ LELYVEGLQD YEAALKIDPS NKIVQIDAEK

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 90%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against DYX1C1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DYX1C1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52548-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details

Target: Dynein Assembly Factor 4, Axonemal (DNAAF4)

Alternative Name: DNAAF4

Background:

Background Information: This gene encodes a tetratricopeptide repeat domain-containing protein. The encoded protein interacts with estrogen receptors and the heat shock proteins, Hsp70 and Hsp90. An homologous protein in rat has been shown to function in neuronal migration in the developing neocortex. A chromosomal translocation involving this gene is associated with a susceptibility to developmental dyslexia. Mutations in this gene are associated with deficits in reading and spelling. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream cell cycle progression 1 (CCPG1) gene.

Gene Name: dynein axonemal assembly factor 4

Alternative Symbols: RD, DYX1, EKN1, DYXC1, CILD25, DYX1C1

Protein Name: dynein assembly factor 4, axonemal

Molecular Weight: 48kDa

Gene ID: 161582

NCBI Accession: NP_570722

UniProt: Q8WXU2