Septin 12 antibody (Middle Region)

Catalog No. ABIN2785054

The Rabbit Polyclonal anti-Septin 12 antibody (ABIN2785054) specifically detects Septin 12 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Guinea Pig, Horse, Dog, Rabbit, Saccharomyces cerevisiae and Zebrafish (Danio rerio) samples.

Quick Overview for Septin 12 antibody (Middle Region) (ABIN2785054)

Target: Septin 12 (Sep12)

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Dog, Rabbit, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Septin 12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Septin 12 Antibody

Binding Specificity: Middle Region

Purpose: SEPT12 Antibody - middle region

Sequence: LQRLCRTVNV VPVIARADSL TMEEREAFRR RIQQNLRTHC IDVYPQMCFD

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 92%, Zebrafish: 91%

Characteristics: This is a rabbit polyclonal antibody against SEPT12. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SEPT12

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52697-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Septin 12

Target: Septin 12 (Sep12)

Alternative Name: SEPT12

Background:

Background Information: Septins, such as SEPT12, are conserved GTP-binding proteins that function as dynamic, regulatable scaffolds for the recruitment of other proteins. They are involved in membrane dynamics, vesicle trafficking, apoptosis, and cytoskeleton remodeling, as well as infection, neurodegeneration, and neoplasia.Septins, such as SEPT12, are conserved GTP-binding proteins that function as dynamic, regulatable scaffolds for the recruitment of other proteins. They are involved in membrane dynamics, vesicle trafficking, apoptosis, and cytoskeleton remodeling, as well as infection, neurodegeneration, and neoplasia (Hall et al., 2005 [PubMed 15915442]).[supplied by OMIM]. Sequence Note: removed 1 base from the 5' end that did not align to the reference genome assembly. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1290 AK058139.1 2-1291

Gene Name: Septin 12

Alternative Symbols: SEPT12, SPGF10

Protein Name: Septin-12

Molecular Weight: 41kDa

Gene ID: 124404

NCBI Accession: NP_653206

UniProt: Q8IYM1