TIRAP antibody (Middle Region)

Catalog No. ABIN2785133

The Rabbit Polyclonal anti-TIRAP antibody (ABIN2785133) specifically detects TIRAP in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Horse, Pig, Dog, Guinea Pig and Rabbit samples.

Quick Overview for TIRAP antibody (Middle Region) (ABIN2785133)

Target: TIRAP (Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP))

Reactivity: Human, Mouse, Rat, Cow, Horse, Pig, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIRAP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TIRAP Antibody

Binding Specificity: Middle Region

Sequence: LEGSTASLRC FLQLRDATPG GAIVSELCQA LSSSHCRVLL ITPGFLQDPW

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against TIRAP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TIRAP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 235 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TIRAP

Target: TIRAP (Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP))

Alternative Name: TIRAP

Background: The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleuk
Alias Symbols: FLJ42305, Mal, wyatt, BACTS1
Protein Interaction Partner: TAB1, TNFSF9, TRAF6, MAP3K7, PCNA, MPP3, APP, KAT2A, BTK, TICAM2, SOCS1, UBC, SAMHD1, IRAK1, ARAF, UBR2, PDS5A, TAB2, SNRNP200, TLR4, STAT3, NF1, JAK1, IRAK2, UBR1, RPTOR, CCDC47, IRAK4, LTN1, TLR2, MYD88, CASP1, RNF216, TICAM1, TRAM1, PRKRA, IL1RL1, DNAJ
Protein Size: 235

Molecular Weight: 25 kDa

Gene ID: 114609

NCBI Accession: NM_148910, NP_683708

UniProt: Q56UH9

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades