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Nesprin3 antibody (N-Term)

C14orf49 Reactivity: Human, Mouse, Rat, Dog, Horse, Pig, Cow, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2785211
  • Target See all Nesprin3 (C14orf49) Antibodies
    Nesprin3 (C14orf49) (Chromosome 14 Open Reading Frame 49 (C14orf49))
    Binding Specificity
    • 15
    • 8
    • 8
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    Human, Mouse, Rat, Dog, Horse, Pig, Cow, Rabbit
    Host
    • 41
    Rabbit
    Clonality
    • 41
    Polyclonal
    Conjugate
    • 17
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Nesprin3 antibody is un-conjugated
    Application
    • 41
    • 18
    • 13
    • 13
    • 13
    • 8
    • 6
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    AQVLLHNVDN QAVLLDRLLE EAASLFNRIG DPSVDEDAQK RMKAEYDAVK
    Predicted Reactivity
    Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 93%
    Characteristics
    This is a rabbit polyclonal antibody against SYNE3. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human SYNE3
    Top Product
    Discover our top product C14orf49 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeat freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Nesprin3 (C14orf49) (Chromosome 14 Open Reading Frame 49 (C14orf49))
    Alternative Name
    SYNE3 (C14orf49 Products)
    Synonyms
    C14orf49 antibody, NET53 antibody, Nesp3 antibody, 4831426I19Rik antibody, nesprin-3 antibody, spectrin repeat containing nuclear envelope family member 3 antibody, spectrin repeat containing, nuclear envelope family member 3 antibody, SYNE3 antibody, Syne3 antibody
    Background
    SYNE3 is a component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. It is involved in the maintenance of nuclear organization and structural integrity. It is a probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. SYNE3 plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells.
    Protein Size: 596
    Molecular Weight
    65 kDa
    Gene ID
    161176
    Pathways
    Maintenance of Protein Location
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