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Aurora Kinase C antibody (Middle Region)

AURKC Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2785453
  • Target See all Aurora Kinase C (AURKC) Antibodies
    Aurora Kinase C (AURKC)
    Binding Specificity
    • 19
    • 9
    • 9
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)
    Host
    • 67
    • 2
    • 1
    Rabbit
    Clonality
    • 70
    Polyclonal
    Conjugate
    • 32
    • 7
    • 6
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Aurora Kinase C antibody is un-conjugated
    Application
    • 63
    • 41
    • 28
    • 13
    • 9
    • 3
    • 1
    Western Blotting (WB)
    Sequence
    TYDEKVDLWC IGVLCYELLV GYPPFESASH SETYRRILKV DVRFPLSMPL
    Predicted Reactivity
    Cow: 93%, Dog: 93%, Goat: 79%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%
    Characteristics
    This is a rabbit polyclonal antibody against AURKC. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human AURKC
    Top Product
    Discover our top product AURKC Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 309 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lee, Lim, Park, Lee, Han, Kim, Cheang, Lee, Lee, Ko, Jang, Kim, Miniaci, Bartsch, Kim, Bailey, Kandel, Kaang: "Nuclear translocation of CAM-associated protein activates transcription for long-term facilitation in Aplysia." in: Cell, Vol. 129, Issue 4, pp. 801-12, (2007) (PubMed).

  • Target
    Aurora Kinase C (AURKC)
    Alternative Name
    AURKC (AURKC Products)
    Synonyms
    AURKC antibody, AIE2 antibody, AIK3 antibody, ARK3 antibody, AurC antibody, SPGF5 antibody, STK13 antibody, aurora-C antibody, AIE1 antibody, ARK-3 antibody, IAK3 antibody, Stk13 antibody, aurora kinase C antibody, AURKC antibody, Aurkc antibody
    Background
    AURKC may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis.This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.
    Alias Symbols: AIE2, AIK3, AurC, STK13, aurora-C, ARK3, SPGF5
    Protein Interaction Partner: SRPK1, AURKB, HIST1H3A, INCENP, BIRC5, TACC2, UBC, HSP90AA1, BRCA1, LNX1, NEDD4L, NEDD4, CENPA,
    Protein Size: 309
    Molecular Weight
    34 kDa
    Gene ID
    6795
    NCBI Accession
    NM_001015878, NP_001015878
    UniProt
    Q9UQB9
    Pathways
    Cell Division Cycle, Maintenance of Protein Location
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