Choline Kinase alpha antibody (Middle Region)

Catalog No. ABIN2785459

The Rabbit Polyclonal anti-Choline Kinase alpha antibody has been validated for WB. It is suitable to detect Choline Kinase alpha in samples from Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig and Horse.

Quick Overview for Choline Kinase alpha antibody (Middle Region) (ABIN2785459)

Target: Choline Kinase alpha (CHKA)

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Choline Kinase alpha antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Choline Kinase alpha Antibody

Binding Specificity: Middle Region

Sequence: LESVMFAILA ERSLGPKLYG IFPQGRLEQF IPSRRLDTEE LSLPDISAEI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CHKA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CHKA

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 457 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Choline Kinase alpha

Target: Choline Kinase alpha (CHKA)

Alternative Name: CHKA

Background: The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. CHKA is the initial enzyme in the sequence and may play a regulatory role. It also catalyzes the phosphorylation of ethanolamine.The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. The protein encoded by this gene is the initial enzyme in the sequence and may play a regulatory role. The encoded protein also catalyzes the phosphorylation of ethanolamine. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CHK, CKI, CK, EK
Protein Interaction Partner: PSEN2, APP, DEPTOR, SKP2, FCHSD2, UBC, RCC1,
Protein Size: 457

Molecular Weight: 50 kDa

Gene ID: 1119

NCBI Accession: NM_001277, NP_001268

UniProt: P35790