SPAG11B antibody (N-Term)

Catalog No. ABIN2785534

The Rabbit Polyclonal anti-SPAG11B antibody is suitable to detect SPAG11B in samples from Human. It has been validated for WB.

Quick Overview for SPAG11B antibody (N-Term) (ABIN2785534)

Target: SPAG11B (Sperm Associated Antigen 11B (SPAG11B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPAG11B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SPAG11B Antibody

Binding Specificity: N-Term

Purpose: SPAG11B Antibody - N-terminal region

Sequence: MRQRLLPSVT SLLLVALLFP GSSQARHVNH SATEALGELR ERAPGQGTNG

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against SPAG11B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SPAG11B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8112589

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SPAG11B

Target: SPAG11B (Sperm Associated Antigen 11B (SPAG11B))

Alternative Name: SPAG11B

Background:

Background Information: SPAG11B is one of several androgen-dependent, epididymis-specific secretory proteins. The specific functions of these proteins have not been determined, but they are thought to be involved in sperm maturation. Some of the isoforms contain regions of similarity to beta-defensins, a family of antimicrobial peptides.This gene encodes several androgen-dependent, epididymis-specific secretory proteins. The specific functions of these proteins have not been determined, but they are thought to be involved in sperm maturation. Some of the isoforms contain regions of similarity to beta-defensins, a family of antimicrobial peptides. The gene is located on chromosome 8p23 near the defensin gene cluster. Alternative splicing of this gene results in seven transcript variants encoding different isoforms. Two different N-terminal and five different C-terminal protein sequences are encoded by the splice variants. Two additional variants have been described, but their full length sequences have not been determined.

Gene Name: Sperm associated antigen 11B

Alternative Symbols: EP2, HE2, EP2C, EP2D, HE2C, EDDM2B, SPAG11, SPAG11A

Protein Name: Sperm-associated antigen 11B

Molecular Weight: 15kDa

Gene ID: 10407

NCBI Accession: NP_478108

UniProt: Q08648