FUCA1 antibody (Middle Region)

Catalog No. ABIN2785640

This Rabbit Polyclonal antibody specifically detects FUCA1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig and Horse.

Quick Overview for FUCA1 antibody (Middle Region) (ABIN2785640)

Target: FUCA1 (Fucosidase, alpha-L- 1, Tissue (FUCA1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FUCA1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FUCA1 Antibody

Binding Specificity: Middle Region

Purpose: FUCA1 Antibody - middle region

Sequence: TNWPSPVSWN WNSKDVGPHR DLVGELGTAL RKRNIRYGLY HSLLEWFHPL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FUCA1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FUCA1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54294-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for FUCA1

Target: FUCA1 (Fucosidase, alpha-L- 1, Tissue (FUCA1))

Alternative Name: FUCA1

Background:

Background Information: Alpha-L-fucosidase (EC 3.2.1.51) is a lysosomal enzyme involved in the degradation of fucose-containing glycoproteins and glycolipids. At least 2 separate polymorphic alpha-L-fucosidases are recognized in man: that in tissues, FUCA1, which is deficient in

Gene Name: Fucosidase, alpha-L- 1, tissue

Alternative Symbols: FUCA

Protein Name: Tissue alpha-L-fucosidase

Molecular Weight: 54kDa

Gene ID: 2517

NCBI Accession: NP_000138

UniProt: P04066

Pathways: Glycosaminoglycan Metabolic Process