Aminomethyltransferase antibody (N-Term)

Catalog No. ABIN2785650

Product Details anti-Aminomethyltransferase Antibody

Target: Aminomethyltransferase (AMT)

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aminomethyltransferase antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QRAVSVVARL GFRLQAFPPA LCRPLSCAQE VLRRTPLYDF HLAHGGKMVA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against AMT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human AMT

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 403 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Aminomethyltransferase

Target: Aminomethyltransferase (AMT)

Alternative Name: AMT (AMT Products)

Synonyms: F16J13.200 antibody, F16J13_200 antibody, T7P1.13 antibody, T7P1_13 antibody, wu:fc31f04 antibody, wu:fd44b12 antibody, wu:fd54h12 antibody, zgc:103483 antibody, zgc:109741 antibody, GCE antibody, GCST antibody, GCVT antibody, NKH antibody, EG434437 antibody, aminomethyltransferase antibody, Glycine cleavage T-protein family antibody, Aminomethyltransferase antibody, aminomethyltransferase L homeolog antibody, AMT antibody, AT4G12130 antibody, AT1G60990 antibody, Tb11.01.1440 antibody, Palpr_0614 antibody, Ocepr_1643 antibody, Celal_2914 antibody, Deima_1002 antibody, Deipr_1956 antibody, Bacsa_3405 antibody, Celly_0288 antibody, Weevi_0527 antibody, Fluta_3952 antibody, Marky_0785 antibody, Spico_1217 antibody, Poras_1228 antibody, Halhy_3617 antibody, amt antibody, amt.L antibody, Amt antibody

Background: The enzyme system for cleavage of glycine (glycine cleavage system, EC 2.1.2.10), which is confined to the mitochondria, is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). Glycine encephalopathy (GCE) may be due to a defect in any one of these enzymes.The enzyme system for cleavage of glycine (glycine cleavage system, EC 2.1.2.10), which is confined to the mitochondria, is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase, MIM 238300), H protein (a lipoic acid-containing protein, MIM 238330), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase, MIM 238331). Glycine encephalopathy (GCE, MIM 605899) may be due to a defect in any one of these enzymes.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2102 D13811.1 1-2102 2103-2117 BC044792.1 3271-3285
Alias Symbols: GCE, GCST, NKH, GCVT
Protein Interaction Partner: HSPA8,
Protein Size: 403

Molecular Weight: 44 kDa

Gene ID: 275

NCBI Accession: NM_000481, NP_000472

UniProt: P48728