IGF2 antibody (C-Term)

Catalog No. ABIN2785661

This Rabbit Polyclonal antibody specifically detects IGF2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Pig, Sheep, Dog, Horse and Goat.

Quick Overview for IGF2 antibody (C-Term) (ABIN2785661)

Target: IGF2 (Insulin-Like Growth Factor 2 (IGF2))

Reactivity: Human, Mouse, Rat, Cow, Pig, Sheep, Dog, Horse, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGF2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IGF2 Antibody

Binding Specificity: C-Term

Purpose: IGF2 Antibody - C-terminal region

Sequence: YDTWKQSTQR LRRGLPALLR ARRGHVLAKE LEAFREAKRH RPLIALPTQD

Predicted Reactivity: Cow: 93%, Dog: 93%, Goat: 93%, Horse: 86%, Human: 100%, Mouse: 92%, Pig: 85%, Rat: 92%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against IGF2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54342-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for IGF2

Target: IGF2 (Insulin-Like Growth Factor 2 (IGF2))

Alternative Name: IGF2

Background:

Background Information: This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: Insulin-like growth factor 2 (somatomedin A)

Alternative Symbols: GRDF, SRS3, IGF-II, PP9974, C11orf43

Protein Name: Insulin-like growth factor II Ala-25 Del Ensembl ENSP00000391826

Molecular Weight: 25kDa

Gene ID: 3481

NCBI Accession: NP_001121070

UniProt: C9JAF2

Pathways: Hormone Activity, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Activated T Cell Proliferation