IMPDH1 antibody (C-Term)

Catalog No. ABIN2785672

This Rabbit Polyclonal antibody specifically detects IMPDH1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio), Rabbit and Saccharomyces cerevisiae.

Quick Overview for IMPDH1 antibody (C-Term) (ABIN2785672)

Target: IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio), Rabbit, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IMPDH1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IMPDH1 Antibody

Binding Specificity: C-Term

Purpose: IMPDH1 Antibody - C-terminal region

Sequence: DGVRLKKYRG MGSLDAMEKS SSSQKRYFSE GDKVKIAQGV SGSIQDKGSI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against IMPDH1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of IMPDH1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54364-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for IMPDH1

Target: IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))

Alternative Name: IMPDH1

Background:

Background Information: The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.

Alternative Symbols: IMPD, RP10, IMPD1, LCA11, IMPDH-I, sWSS2608

Protein Name: Inosine-5'-monophosphate dehydrogenase 1

Molecular Weight: 63kDa

Gene ID: 3614

NCBI Accession: NP_001096075

UniProt: P20839

Pathways: Ribonucleoside Biosynthetic Process