MAGEA4 antibody (C-Term)

Catalog No. ABIN2785699

The Rabbit Polyclonal anti-MAGEA4 antibody is suitable to detect MAGEA4 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig and Rabbit. It has been validated for WB.

Quick Overview for MAGEA4 antibody (C-Term) (ABIN2785699)

Target: MAGEA4 (Melanoma Antigen Family A, 4 (MAGEA4))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGEA4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MAGEA4 Antibody

Binding Specificity: C-Term

Purpose: MAGEA4 Antibody - C-terminal region

Sequence: ENYLEYRQVP GSNPARYEFL WGPRALAETS YVKVLEHVVR VNARVRIAYP

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 93%, Rabbit: 79%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against MAGEA4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MAGEA4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8105083

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAGEA4

Target: MAGEA4 (Melanoma Antigen Family A, 4 (MAGEA4))

Alternative Name: MAGEA4

Background:

Background Information: MAGEA4 is a member of the MAGEA family. The members of this family are proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. At least four variants encoding the same protein have been found for this gene.

Gene Name: Melanoma antigen family A, 4

Alternative Symbols: CT1.4, MAGE4, MAGE4A, MAGE4B, MAGE-41, MAGE-X2

Protein Name: Melanoma-associated antigen 4

Molecular Weight: 35kDa

Gene ID: 4103

NCBI Accession: NP_001011548

UniProt: P43358