Fibromodulin antibody (N-Term)

Catalog No. ABIN406405

This Rabbit Polyclonal antibody specifically detects Fibromodulin in WB. It exhibits reactivity toward Human, Rat, Mouse, Guinea Pig, Horse, Cow, Dog and Rabbit.

Quick Overview for Fibromodulin antibody (N-Term) (ABIN406405)

Target: Fibromodulin (FMOD)

Reactivity: Human, Rat, Mouse, Guinea Pig, Horse, Cow, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fibromodulin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Fibromodulin Antibody

Binding Specificity: N-Term

Sequence: VYFQNNQITS IQEGVFDNAT GLLWIALHGN QITSDKVGRK VFSKLRHLER

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FMOD. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FMOD

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 376 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Fibromodulin

Target: Fibromodulin (FMOD)

Alternative Name: FMOD

Background: Fibromodulin is a member of a family of small interstitial proteoglycans, containing a central region composed of leucine-rich repeats with 4 keratan sulfate chains flanked by disulfide-bonded terminal domains. It may participate in the assembly of the extracellular matrix as it interacts with type I and type II collagen fibrils and inhibits fibrillogenesis in vitro. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix.Fibromodulin is a member of a family of small interstitial proteoglycans, containing a central region composed of leucine-rich repeats with 4 keratan sulfate chains flanked by disulfide-bonded terminal domains. It may participate in the assembly of the extracellular matrix as it interacts with type I and type II collagen fibrils and inhibits fibrillogenesis in vitro. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: SLRR2E
Protein Interaction Partner: BTBD1, ZBTB32, CUL3, Dlg4, TGFB3, TGFB2, TGFB1,
Protein Size: 376

Molecular Weight: 43 kDa

Gene ID: 2331

NCBI Accession: NM_002023, NP_002014

UniProt: Q06828

Pathways: Glycosaminoglycan Metabolic Process