GNAQ antibody (N-Term)

Catalog No. ABIN2785811

This Rabbit Polyclonal antibody specifically detects GNAQ in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for GNAQ antibody (N-Term) (ABIN2785811)

Target: GNAQ (Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNAQ antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GNAQ Antibody

Binding Specificity: N-Term

Sequence: DKRGFTKLVY QNIFTAMQAM IRAMDTLKIP YKYEHNKAHA QLVREVDVEK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against GNAQ. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GNAQ

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 359 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GNAQ

Target: GNAQ (Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ))

Alternative Name: GNAQ

Background: Guanine nucleotide-binding proteins are a family of heterotrimeric proteins that couple cell surface, 7-transmembrane domain receptors to intracellular signaling pathways. Receptor activation catalyzes the exchange of GTP for GDP bound to the inactive G p
Alias Symbols: G-ALPHA-q, GAQ
Protein Interaction Partner: AIP, UBC, GNB3, TBXA2R, IQSEC1, CYTH1, CYTH3, PSD, PLCB2, PLCB1, CYTH2, PTGIR, ARF6, WDR36, RIC8A, ADRBK1, ATP4A, NT5C3A, PPT1, LUM, Agtr1a, ADHFE1, CDK19, GNAS, MRGPRX1, F2R, Ric8b, TTC1, CRHR1, RGS18, RGS13, S1PR2, SLC9A3R1, AKAP13, GRM7, GRM4, GRM2, FF
Protein Size: 359

Molecular Weight: 42 kDa

Gene ID: 2776

NCBI Accession: NM_002072, NP_002063

UniProt: P50148

Pathways: JAK-STAT Signaling, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction