HABP2 antibody (Middle Region)

Catalog No. ABIN2785849

The Rabbit Polyclonal anti-HABP2 antibody (ABIN2785849) specifically detects HABP2 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Horse, Rabbit, Guinea Pig and Cow samples.

Quick Overview for HABP2 antibody (Middle Region) (ABIN2785849)

Target: HABP2 (Hyaluronan Binding Protein 2 (HABP2))

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Guinea Pig, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HABP2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HABP2 Antibody

Binding Specificity: Middle Region

Purpose: HABP2 Antibody - middle region

Sequence: EPSTKLPGFD SCGKTEIAER KIKRIYGGFK STAGKHPWQA SLQSSLPLTI

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HABP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HABP2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54718-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HABP2

Target: HABP2 (Hyaluronan Binding Protein 2 (HABP2))

Alternative Name: HABP2

Background:

Background Information: HABP2 is an extracellular serine protease that binds hyaluronic acid and is involved in cell adhesion. It is synthesized as a single chain, but then undergoes an autoproteolytic event to form the functional heterodimer. Further autoproteolysis leads to smaller, inactive peptides. This protease is known to cleave urinary plasminogen activator, coagulation factor VII, and the alpha and beta chains of fibrinogen, but not prothrombin, plasminogen, or the gamma chain of fibrinogen. The protein encoded by this gene is an extracellular serine protease that binds hyaluronic acid and is involved in cell adhesion. The encoded protein is synthesized as a single chain, but then undergoes an autoproteolytic event to form the functional heterodimer. Further autoproteolysis leads to smaller, inactive peptides. This protease is known to cleave urinary plasminogen activator, coagulation factor VII, and the alpha and beta chains of fibrinogen, but not prothrombin, plasminogen, or the gamma chain of fibrinogen. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Hyaluronan binding protein 2

Alternative Symbols: FSAP, HABP, PHBP, HGFAL, NMTC5

Protein Name: Hyaluronan-binding protein 2

Molecular Weight: 63kDa

Gene ID: 3026

NCBI Accession: NP_004123

UniProt: Q14520