COG2 antibody (N-Term)

Catalog No. ABIN2785901

The Rabbit Polyclonal anti-COG2 antibody is suitable to detect COG2 in samples from Human, Mouse, Rat, Horse, Rabbit, Zebrafish (Danio rerio), Cow and Guinea Pig. It has been validated for WB.

Quick Overview for COG2 antibody (N-Term) (ABIN2785901)

Target: COG2 (Conserved oligomeric Golgi complex subunit 2 (COG2))

Reactivity: Human, Mouse, Rat, Horse, Rabbit, Zebrafish (Danio rerio), Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COG2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-COG2 Antibody

Binding Specificity: N-Term

Purpose: COG2 Antibody - N-terminal region

Sequence: KRVQLEELRD DLELYYKLLK TAMVELINKD YADFVNLSTN LVGMDKALNQ

Predicted Reactivity: Cow: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against COG2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human COG2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54815-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for COG2

Target: COG2 (Conserved oligomeric Golgi complex subunit 2 (COG2))

Alternative Name: COG2

Background:

Targeted Subunit: 2

Background Information: Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Golgi transport complex (GTC), the LDLC complex, which is involved in glycosylation reactions, and the SEC34 complex, which is involved in vesicular transport. These 3 complexes are identical and have been termed the conserved oligomeric Golgi (COG) complex, which includes COG2. Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Golgi transport complex (GTC), the LDLC complex, which is involved in glycosylation reactions, and the SEC34 complex, which is involved in vesicular transport. These 3 complexes are identical and have been termed the conserved oligomeric Golgi (COG) complex, which includes COG2 (Ungar et al., 2002 [PubMed 11980916]).[supplied by OMIM].

Gene Name: Component of oligomeric golgi complex 2

Alternative Symbols: LDLC, CDG2Q

Protein Name: Conserved oligomeric Golgi complex subunit 2

Molecular Weight: 83kDa

Gene ID: 22796

NCBI Accession: NP_031383

UniProt: Q14746