TIMM13 antibody (N-Term)

Catalog No. ABIN2785946

This Rabbit Polyclonal antibody specifically detects TIMM13 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Guinea Pig, Horse and Zebrafish (Danio rerio).

Quick Overview for TIMM13 antibody (N-Term) (ABIN2785946)

Target: TIMM13 (Translocase of Inner Mitochondrial Membrane 13 Homolog (TIMM13))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIMM13 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TIMM13 Antibody

Binding Specificity: N-Term

Purpose: Timm13 Antibody - N-terminal region

Sequence: FGSDFGGTGG GKLDPGAIME QVKVQIAVAN AQELLQRMTD KCFRKCIGKP

Predicted Reactivity: Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against Timm13. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54905-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TIMM13

Target: TIMM13 (Translocase of Inner Mitochondrial Membrane 13 Homolog (TIMM13))

Alternative Name: Timm13

Background:

Targeted Subunit: Tim13

Background Information: Timm13 is a mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. It is also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. It acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins.

Gene Name: Translocase of inner mitochondrial membrane 13 homolog (yeast)

Alternative Symbols: Tim, Tim9, Timm, Timm9, D10Ertd378, D10Ertd378e

Protein Name: Mitochondrial import inner membrane translocase subunit Tim13

Molecular Weight: 10kDa

Gene ID: 30055

NCBI Accession: NP_038923

UniProt: P62075

Pathways: Sensory Perception of Sound