PNMA3 antibody (N-Term)

Catalog No. ABIN2785968

This Rabbit Polyclonal antibody specifically detects PNMA3 in WB. It exhibits reactivity toward Human, Rat and Horse.

Quick Overview for PNMA3 antibody (N-Term) (ABIN2785968)

Target: PNMA3 (Paraneoplastic Antigen MA3 (PNMA3))

Reactivity: Human, Rat, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PNMA3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PNMA3 Antibody

Binding Specificity: N-Term

Purpose: PNMA3 Antibody - N-terminal region

Sequence: QDIDYALLPR EIPGKGGPWE VIVKPRNSDG EFLNRLNRFL EEERRTVSDM

Predicted Reactivity: Horse: 93%, Human: 100%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against PNMA3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PNMA3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54945-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PNMA3

Target: PNMA3 (Paraneoplastic Antigen MA3 (PNMA3))

Alternative Name: PNMA3

Background:

Background Information: The specific function of the protein remains unknown.This gene is a member of the paraneoplastic antigen MA (PNMA) gene family, whose protein products share homology with retroviral Gag proteins. They are highly expressed in the brain and also in a range of tumors associated with serious neurological phenotypes. PMID:16407312 reports the presence of a functional -1 ribosomal frameshift signal (consisting of a heptanucleotide shift motif followed 3' by a pseudoknot structure) in this gene, however, the frame-shifted product has not been characterized.

Gene Name: Paraneoplastic Ma antigen 3

Alternative Symbols: MA3, MA5

Protein Name: Paraneoplastic antigen Ma3

Molecular Weight: 52kDa

Gene ID: 29944

NCBI Accession: NP_037496

UniProt: Q9UL41