SMUG1 antibody (Middle Region)

Catalog No. ABIN503627

The Rabbit Polyclonal anti-SMUG1 antibody is suitable to detect SMUG1 in samples from Human, Mouse, Rat, Horse, Pig, Cow, Dog, Guinea Pig and Rabbit. It has been validated for WB.

Quick Overview for SMUG1 antibody (Middle Region) (ABIN503627)

Target: SMUG1 (Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1))

Reactivity: Human, Mouse, Rat, Horse, Pig, Cow, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMUG1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SMUG1 Antibody

Binding Specificity: Middle Region

Sequence: IVGPVLTPPQ EHPKRPVLGL ECPQSEVSGA RFWGFFRNLC GQPEVFFHHC

Predicted Reactivity: Cow: 93%, Dog: 91%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against SMUG1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SMUG1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 270 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SMUG1

Target: SMUG1 (Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1))

Alternative Name: SMUG1

Background: SMUG1 is a glycosylase that removes uracil from single- and double-stranded DNA in nuclear chromatin, thus contributing to base excision repair.SMUG1 is a glycosylase that removes uracil from single- and double-stranded DNA in nuclear chromatin, thus contributing to base excision repair.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FDG, HMUDG, MGC104370, UNG3
Protein Interaction Partner: VAC14, UNG, vpr, UBC, RBPMS, TRIP13,
Protein Size: 270

Molecular Weight: 30 kDa

Gene ID: 23583

NCBI Accession: NM_014311, NP_055126

UniProt: Q53HV7

Pathways: DNA Damage Repair