SH3BP4 antibody (N-Term)

Catalog No. ABIN2786040

This Rabbit Polyclonal antibody specifically detects SH3BP4 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Zebrafish (Danio rerio), Guinea Pig, Rabbit and Pig.

Quick Overview for SH3BP4 antibody (N-Term) (ABIN2786040)

Target: SH3BP4 (SH3-Domain Binding Protein 4 (SH3BP4))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Zebrafish (Danio rerio), Guinea Pig, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH3BP4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SH3BP4 Antibody

Binding Specificity: N-Term

Sequence: FTTLKFSKGD HLYVLDTSGG EWWYAHNTTE MGYIPSSYVQ PLNYRNSTLS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against SH3BP4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SH3BP4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 963 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SH3BP4

Target: SH3BP4 (SH3-Domain Binding Protein 4 (SH3BP4))

Alternative Name: SH3BP4

Background: This gene encodes a protein with 3 Asn-Pro-Phe (NPF) motifs, an SH3 domain, a PXXP motif, a bipartite nuclear targeting signal, and a tyrosine phosphorylation site. This protein is involved in cargo-specific control of clathrin-mediated endocytosis, specifically controlling the internalization of a specific protein receptor.
Alias Symbols: BOG25, TTP
Protein Interaction Partner: UBC, MYC, SH3BP4, TFRC, TFAP2A, EPS15, DNM1, C2orf73, ZBTB37, CEP78, GKAP1, PRR14, PLEKHA1, DNAJA4, MRGBP, MPHOSPH8, NFU1, GAPDHS, CIZ1, TXNL1, TTC1, CCT3, TCP1, PSMA1, HSPA5, FKBP4, YWHAG, YWHAE, YWHAQ, SFN, GIPC1,
Protein Size: 963

Molecular Weight: 107 kDa

Gene ID: 23677

NCBI Accession: NM_014521, NP_055336

UniProt: Q9P0V3