SH3BP4 antibody

Catalog No. ABIN7231346

The Rabbit Polyclonal anti-SH3BP4 antibody is suitable to detect SH3BP4 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for SH3BP4 antibody (ABIN7231346)

Target: SH3BP4 (SH3-Domain Binding Protein 4 (SH3BP4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH3BP4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SH3BP4 Antibody

Purpose: Rabbit Anti-SH3B4 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of SH3B4 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human SH3B4 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SH3BP4

Target: SH3BP4 (SH3-Domain Binding Protein 4 (SH3BP4))

Alternative Name: SH3B4

Background: SH3 domain-binding protein 4, EH-binding protein 10, Transferrin receptor-trafficking proteinSH3BP4 (SH3 Domain Binding Protein 4) is a Protein Coding gene. Diseases associated with SH3BP4 include Cataract 8, Multiple Types. Among its related pathways are PI3K / Akt Signaling. SH3BP4 encodes a protein with 3 Asn-Pro-Phe (NPF) motifs, an SH3 domain, a PXXP motif, a bipartite nuclear targeting signal, and a tyrosine phosphorylation site. This protein is involved in cargo-specific control of clathrin-mediated endocytosis, specifically controlling the internalization of a specific protein receptor.

Molecular Weight: 105kD

Gene ID: 23677

UniProt: Q9P0V3