DAAM1 antibody (Middle Region)
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- Target See all DAAM1 Antibodies
- DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Rabbit, Zebrafish (Danio rerio), Cow, Guinea Pig, Horse, Dog
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DAAM1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- GNTVQYWLLL DRIIQQIVIQ NDKGQDPDST PLENFNIKNV VRMLVNENEV
- Predicted Reactivity
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
- Characteristics
- This is a rabbit polyclonal antibody against DAAM1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human DAAM1
- Top Product
- Discover our top product DAAM1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 1078 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))
- Alternative Name
- DAAM1 (DAAM1 Products)
- Synonyms
- 1700066F09Rik antibody, 2310028E21Rik antibody, AI503486 antibody, E130308H01 antibody, mKIAA0666 antibody, daam-1 antibody, xdaam1 antibody, daam1 antibody, DAAM1 antibody, DKFZp468D0524 antibody, daam1l antibody, fc83b10 antibody, si:ch211-87i20.1 antibody, wu:fc83b10 antibody, dishevelled associated activator of morphogenesis 1 antibody, dishevelled associated activator of morphogenesis 1 S homeolog antibody, dishevelled associated activator of morphogenesis 1a antibody, dishevelled associated activator of morphogenesis 1b antibody, DAAM1 antibody, Daam1 antibody, daam1.S antibody, daam1a antibody, daam1 antibody, daam1b antibody
- Background
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Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton and recent evidence suggests a role for the Formin homology (FH) proteins in these processes. The protein encoded by this gene contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by this gene product, which is thought to function as a scaffolding protein.Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton and recent evidence suggests a role for the Formin homology (FH) proteins in these processes. The protein encoded by this gene contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by this gene product, which is thought to function as a scaffolding protein. Evidence of alternative splicing has been observed for this gene but the full-length nature of these variants has not been determined.
Alias Symbols: FLJ41657, KIAA0666
Protein Interaction Partner: UBC, PRPF40A, B3GALT4, AMBP, MAP3K7, DVL2, DVL1, RHOA,
Protein Size: 1078 - Molecular Weight
- 123 kDa
- Gene ID
- 23002
- NCBI Accession
- NM_014992, NP_055807
- UniProt
- Q9Y4D1
- Pathways
- WNT Signaling
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