FANCE antibody (Middle Region)
-
- Target See all FANCE Antibodies
- FANCE (Fanconi Anemia, Complementation Group E (FANCE))
-
Binding Specificity
- Middle Region
- Reactivity
- Human, Cow, Rabbit, Horse, Pig, Dog
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This FANCE antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Sequence
- SPQAPDPEEE ENRDSQQPGK RRKDSEEEAA SPEGKRVPKR LRCWEEEEDH
- Predicted Reactivity
- Cow: 86%, Dog: 79%, Horse: 85%, Human: 100%, Pig: 79%, Rabbit: 79%
- Characteristics
- This is a rabbit polyclonal antibody against FANCE. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human FANCE
- Top Product
- Discover our top product FANCE Primary Antibody
-
-
- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
-
Antigen size: 536 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- FANCE (Fanconi Anemia, Complementation Group E (FANCE))
- Alternative Name
- FANCE (FANCE Products)
- Synonyms
- FANCE antibody, fae antibody, face antibody, FACE antibody, FAE antibody, 2810451D06Rik antibody, AI415634 antibody, AW209126 antibody, RGD1561045 antibody, Fanconi anemia complementation group E antibody, Fanconi anemia, complementation group E antibody, FANCE antibody, fance antibody, Fance antibody
- Background
-
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex.The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group E. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FACE, FAE
Protein Interaction Partner: APITD1, STRA13, UBC, FANCG, FANCD2, FANCC, FANCA, FANCM, C1orf86, ELAVL1, Erh, FANCF, CHEK1, HES1, PCNA, BRCA2,
Protein Size: 536 - Molecular Weight
- 59 kDa
- Gene ID
- 2178
- NCBI Accession
- NM_021922, NP_068741
- UniProt
- Q9HB96
- Pathways
- DNA Damage Repair
-