HIPK1 antibody (Middle Region)

Catalog No. ABIN2786406

The Rabbit Polyclonal anti-HIPK1 antibody (ABIN2786406) specifically detects HIPK1 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse and Rabbit samples.

Quick Overview for HIPK1 antibody (Middle Region) (ABIN2786406)

Target: HIPK1 (Homeodomain Interacting Protein Kinase 1 (HIPK1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIPK1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HIPK1 Antibody

Binding Specificity: Middle Region

Purpose: HIPK1 Antibody - middle region

Sequence: PLNLSQNQQS SAAPTSQERS SNPAPRRQQA FVAPLSQAPY TFQHGSPLHS

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against HIPK1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HIPK1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55866-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HIPK1

Target: HIPK1 (Homeodomain Interacting Protein Kinase 1 (HIPK1))

Alternative Name: HIPK1

Background:

Background Information: HIPK1 may play a role as a corepressor for homeodomain transcription factors. HIPK1 phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. HIPK1 may be involved in malignant squamous cell tumor formation.The protein encoded by this gene belongs to the Ser/Thr family of protein kinases and HIPK subfamily. It phosphorylates homeodomain transcription factors and may also function as a co-repressor for homeodomain transcription factors. Alternative splicing results in four transcript variants encoding four distinct isoforms.

Gene Name: Homeodomain interacting protein kinase 1

Alternative Symbols: Myak, Nbak2

Protein Name: Homeodomain-interacting protein kinase 1

Molecular Weight: 131kDa

Gene ID: 204851

NCBI Accession: NP_938009

UniProt: Q86Z02