PPP3R1 antibody (N-Term)

Catalog No. ABIN2786524

This Rabbit Polyclonal antibody specifically detects PPP3R1 in WB. It exhibits reactivity toward Human, Rat, Mouse, Cow, Zebrafish (Danio rerio), Guinea Pig, Horse, Rabbit and Dog.

Quick Overview for PPP3R1 antibody (N-Term) (ABIN2786524)

Target: PPP3R1 (Protein Phosphatase 3, Regulatory Subunit B, alpha (PPP3R1))

Reactivity: Human, Rat, Mouse, Cow, Zebrafish (Danio rerio), Guinea Pig, Horse, Rabbit, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP3R1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PPP3R1 Antibody

Binding Specificity: N-Term

Sequence: MGNEASYPLE MCSHFDADEI KRLGKRFKKL DLDNSGSLSV EEFMSLPELQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against PPP3R1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PPP3R1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 170 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PPP3R1

Target: PPP3R1 (Protein Phosphatase 3, Regulatory Subunit B, alpha (PPP3R1))

Alternative Name: PPP3R1

Background: PPP3R1 is the regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. PPP3R1 confers calcium sensitivity.
Alias Symbols: CALNB1, CNB, CNB1
Protein Interaction Partner: PPP3CA, TP53, IQCB1, UBC, NAP1L2, TRAF3, PDE4D, PSMA7, ELAVL1, CABP2, MAP3K5, NFATC2, NFATC1, FKBP1A, PPIA, CABP5, CABP1, CRTC1,
Protein Size: 170

Molecular Weight: 19 kDa

Gene ID: 5534

NCBI Accession: NM_000945, NP_000936

UniProt: P63098

Pathways: RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, Protein targeting to Nucleus, VEGF Signaling, BCR Signaling