PPP2CA antibody (N-Term)

Catalog No. ABIN2786564

The Rabbit Polyclonal anti-PPP2CA antibody is suitable to detect PPP2CA in samples from Human, Mouse, Rat, Cow, Rabbit, Zebrafish (Danio rerio), Dog, Guinea Pig, Horse, Saccharomyces cerevisiae and Sheep. It has been validated for WB.

Quick Overview for PPP2CA antibody (N-Term) (ABIN2786564)

Target: PPP2CA (Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA))

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Zebrafish (Danio rerio), Dog, Guinea Pig, Horse, Saccharomyces cerevisiae, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP2CA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PPP2CA Antibody

Binding Specificity: N-Term

Sequence: FHDLMELFRI GGKSPDTNYL FMGDYVDRGY YSVETVTLLV ALKVRYRERI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 93%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against PPP2CA. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PPP2CA

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PPP2CA

Target: PPP2CA (Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA))

Alternative Name: PPP2CA

Background: This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit.
Protein Interaction Partner: ZFP36, UBC, MID1, VAC14, SETBP1, PPP2R1A, SUMO2, ESPL1, HTT, VCP, ZNF346, NEDD8, SUMO1, RPA3, RPA2, RPA1, HNRNPH1, NIF3L1, TNPO3, AHCYL1, ARPC4, SSB, PFDN1, NRD1, TNPO1, IGBP1, XRN1, TRIP13, BAG3, STK26, CHEK2, STK25, POLA1, NPM1, STK24, CTDP1, RAF1, ID1,
Protein Size: 255

Molecular Weight: 28 kDa

Gene ID: 5515

Pathways: PI3K-Akt Signaling, Mitotic G1-G1/S Phases, Hepatitis C, Toll-Like Receptors Cascades