RAP1A antibody (Middle Region)

Catalog No. ABIN2786569

The Rabbit Polyclonal anti-RAP1A antibody (ABIN2786569) specifically detects RAP1A in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Horse, Dog, Goat and Zebrafish (Danio rerio) samples.

Quick Overview for RAP1A antibody (Middle Region) (ABIN2786569)

Target: RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Horse, Dog, Goat, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAP1A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RAP1A Antibody

Binding Specificity: Middle Region

Purpose: Rap1a Antibody - middle region

Sequence: DLYMKNGQGF ALVYSITAQS TFNDLQDLRE QILRVKDTED VPMILVGNKC

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against Rap1a. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Mouse Rap1a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56195-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for RAP1A

Target: RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))

Alternative Name: Rap1a

Background:

Background Information: Rap1a induces morphological reversion of a cell line transformed by a Ras oncogene. Rap1a counteracts the mitogenic function of Ras, at least partly because it can interact with Ras GAPs and RAF in a competitive manner.

Gene Name: RAP1B, member of RAS oncogene family

Alternative Symbols: R, Krev, Rap1, G-22K, Krev-1, AI848598

Protein Name: Ras-related protein Rap-1A

Molecular Weight: 20kDa

Gene ID: 109905

NCBI Accession: NP_663516

UniProt: P62835

Pathways: TCR Signaling, Neurotrophin Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor