FANCL antibody (Middle Region)

Catalog No. ABIN2786637

The Rabbit Polyclonal anti-FANCL antibody (ABIN2786637) specifically detects FANCL in WB and IHC. The antibody is reactive with Human, Dog and Rabbit samples.

Quick Overview for FANCL antibody (Middle Region) (ABIN2786637)

Target: FANCL (Fanconi Anemia, Complementation Group L (FANCL))

Reactivity: Human, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-FANCL Antibody

Binding Specificity: Middle Region

Purpose: FANCL Antibody - middle region

Sequence: ASGREHLITL KLKAKYPAES PDYFVDFPVP FCASWTPQVN SPQSSLISIY

Predicted Reactivity: Dog: 93%, Human: 100%, Rabbit: 86%

Characteristics: This is a rabbit polyclonal antibody against FANCL. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FANCL

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56321-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for FANCL

Target: FANCL (Fanconi Anemia, Complementation Group L (FANCL))

Alternative Name: FANCL

Background:

Background Information: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FAN

Gene Name: Fanconi anemia, complementation group L

Alternative Symbols: POG, PHF9, FAAP43

Protein Name: E3 ubiquitin-protein ligase FANCL

Molecular Weight: 43 kDa

Gene ID: 55120

NCBI Accession: NP_001108108

UniProt: Q9NW38

Pathways: DNA Damage Repair