MARK3 antibody (Middle Region)

Catalog No. ABIN2786651

The Rabbit Polyclonal anti-MARK3 antibody has been validated for WB. It is suitable to detect MARK3 in samples from Human, Mouse, Rat, Horse, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig and Rabbit.

Quick Overview for MARK3 antibody (Middle Region) (ABIN2786651)

Target: MARK3 (MAP/microtubule Affinity-Regulating Kinase 3 (MARK3))

Reactivity: Human, Mouse, Rat, Horse, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARK3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MARK3 Antibody

Binding Specificity: Middle Region

Sequence: ATYNGPPASP SLSHEATPLS QTRSRGSTNL FSKLTSKLTR SRNVSAEQKD

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against MARK3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MARK3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 729 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MARK3

Target: MARK3 (MAP/microtubule Affinity-Regulating Kinase 3 (MARK3))

Alternative Name: MARK3

Background: MARK3 is involved in the specific phosphorylation of microtubule-associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C on 'Ser-216'.
Alias Symbols: CTAK1, KP78, PAR1A, Par-1a
Protein Interaction Partner: Crtc2, UBC, MAPT, YWHAZ, YWHAH, YWHAG, YWHAE, YWHAB, YWHAQ, SFN, ASB13, TCEA2, PIM1, MARK3, CDC25C, KSR1, USP21, PKP2, MAP2, MITF, PRKAA1, TADA2A, TERF2, HDAC7, HDAC5, HDAC4, MARK2, SAAL1, ANKRD7, VPS11, PNPLA2, NOL11, PMPCB, CHGB, FANCF, CPSF4, DYNLL1, P
Protein Size: 729

Molecular Weight: 81 kDa

Gene ID: 4140

NCBI Accession: NM_002376, NP_002367

Pathways: SARS-CoV-2 Protein Interactome