NPTX2 antibody (N-Term)

Catalog No. ABIN2786662

The Rabbit Polyclonal anti-NPTX2 antibody (ABIN2786662) specifically detects NPTX2 in WB. The antibody is reactive with Human, Rat, Mouse, Dog, Guinea Pig and Cow samples.

Quick Overview for NPTX2 antibody (N-Term) (ABIN2786662)

Target: NPTX2 (Neuronal Pentraxin II (NPTX2))

Reactivity: Human, Rat, Mouse, Dog, Guinea Pig, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPTX2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NPTX2 Antibody

Binding Specificity: N-Term

Purpose: NPTX2 Antibody - N-terminal region

Sequence: VQQKETLGAQ REAIRELTGK LARCEGLAGG KARGAGATGK DTMGDLPRDP

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against NPTX2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NPTX2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56365-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for NPTX2

Target: NPTX2 (Neuronal Pentraxin II (NPTX2))

Alternative Name: NPTX2

Background:

Background Information: This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD.

Gene Name: Neuronal pentraxin II

Alternative Symbols: NP2, NARP, NP-II

Protein Name: Neuronal pentraxin-2

Molecular Weight: 47kDa

Gene ID: 4885

NCBI Accession: NP_002514

UniProt: P47972