MAPK13 antibody (Middle Region)

Catalog No. ABIN2786702

Product Details anti-MAPK13 Antibody

Target: MAPK13 (Mitogen-Activated Protein Kinase 13 (MAPK13))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow, Sheep, Goat, Guinea Pig, Rabbit, Zebrafish (Danio rerio), Horse, Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAPK13 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EMLTGKTLFK GKDYLDQLTQ ILKVTGVPGT EFVQKLNDKA AKSYIQSLPQ

Predicted Reactivity: Cow: 100%, Dog: 93%, Goat: 93%, Guinea Pig: 93%, Horse: 77%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 85%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against MAPK13. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MAPK13

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 365 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAPK13

Target: MAPK13 (Mitogen-Activated Protein Kinase 13 (MAPK13))

Alternative Name: MAPK13 (MAPK13 Products)

Background: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and cellular stress. MAP kinase kinases 3, and 6 can phosphorylate and activate this kinase. Transcription factor ATF2, and microtubule dynamics regulator stathmin have been shown to be the substrates of this kinase.
Alias Symbols: MGC99536, PRKM13, SAPK4, p38delta
Protein Interaction Partner: MAPK13, MAPT, SMAD4, GPX4, VCP, APP, HTRA2, MBP, UBC, AKIP1, ANKLE2, MAPKAPK5, EEF2K, MAP3K4, MAPKAPK3, MAP2K6, ATF2, MAPK8IP2, FGF12,
Protein Size: 365

Molecular Weight: 42 kDa

Gene ID: 5603

NCBI Accession: NM_002754, NP_002745

UniProt: Q9N272

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway, Hepatitis C, BCR Signaling, S100 Proteins