PSMD3 antibody (N-Term)

Catalog No. ABIN2786726

The Rabbit Polyclonal anti-PSMD3 antibody has been validated for WB. It is suitable to detect PSMD3 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit. There is 1 publication available.

Quick Overview for PSMD3 antibody (N-Term) (ABIN2786726)

Target: PSMD3 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 3 (PSMD3))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMD3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PSMD3 Antibody

Binding Specificity: N-Term

Sequence: RLNHYVLYKA VQGFFTSNNA TRDFLLPFLE EPMDTEADLQ FRPRTGKAAS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PSMD3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PSMD3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 534 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-PSMD3 antibody (ABIN2786726)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Target Details for PSMD3

Target: PSMD3 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 3 (PSMD3))

Alternative Name: PSMD3

Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits a
Alias Symbols: P58, RPN3, S3, TSTA2
Protein Interaction Partner: CEP44, ZBTB43, HUWE1, SHFM1, SPRTN, SNAI2, STAU1, PSMD14, UBC, UBQLN1, FLNC, FLNB, PSMD8, PSMD4, PSMD1, PSMC6, PSMC5, PSMC4, PSMC3, PSMC2, PSMC1, KCMF1, UCHL5, KIAA0368, ADRM1, TXNL1, SQSTM1, RPS28, RPS21, RPS15A, RPS13, RPS8, PSMD12, PSMD11, PARK2, FBXO6
Protein Size: 534

Molecular Weight: 61 kDa

Gene ID: 5709

NCBI Accession: NM_002809, NP_002800

UniProt: O43242

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway