MAPK12 antibody (C-Term)

Catalog No. ABIN2786760

The Rabbit Polyclonal anti-MAPK12 antibody (ABIN2786760) specifically detects MAPK12 in WB. The antibody is reactive with Human, Mouse, Rat, Rabbit, Guinea Pig, Cow, Horse and Dog samples.

Quick Overview for MAPK12 antibody (C-Term) (ABIN2786760)

Target: MAPK12 (Mitogen-Activated Protein Kinase 12 (MAPK12))

Reactivity: Human, Mouse, Rat, Rabbit, Guinea Pig, Cow, Horse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAPK12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MAPK12 Antibody

Binding Specificity: C-Term

Purpose: Mapk12 Antibody - C-terminal region

Sequence: ERMLVLDAEQ RVTAAEALTH PYFESLRDTE DEPKAQKYDD SFDDVDRTLE

Predicted Reactivity: Cow: 79%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against Mapk12. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56536-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAPK12

Target: MAPK12 (Mitogen-Activated Protein Kinase 12 (MAPK12))

Alternative Name: Mapk12

Background:

Background Information: Mapk12 responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating downstream targets. Mapk12 plays a role in myoblast differentiation and also in the down-regulation of cyclin D1 in response to hypoxia in adrenal cells suggesting MAPK12 may inhibit cell proliferation while promoting differentiation.

Gene Name: Mitogen-activated protein kinase 12

Alternative Symbols: Sa, Erk, Erk6, Prkm, P38ga, Sapk3, Prkm12, AW123708, P38gamma

Protein Name: Mitogen-activated protein kinase 12

Molecular Weight: 40kDa

Gene ID: 29857

NCBI Accession: NP_038899

UniProt: O08911

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C, BCR Signaling, S100 Proteins