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SH3BP2 antibody (Middle Region)

SH3BP2 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2786764
  • Target See all SH3BP2 Antibodies
    SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))
    Binding Specificity
    • 7
    • 7
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit
    Host
    • 35
    • 4
    • 2
    Rabbit
    Clonality
    • 39
    • 2
    Polyclonal
    Conjugate
    • 22
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SH3BP2 antibody is un-conjugated
    Application
    • 28
    • 20
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    RQPSQADTGG DDSDEDYEKV PLPNSVFVNT TESCEVERLF KATSPRGEPQ
    Predicted Reactivity
    Cow: 85%, Dog: 93%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against SH3BP2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human SH3BP2
    Top Product
    Discover our top product SH3BP2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 561 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))
    Alternative Name
    SH3BP2 (SH3BP2 Products)
    Synonyms
    SH3BP2 antibody, 3BP-2 antibody, 3BP2 antibody, CRBM antibody, CRPM antibody, SH3 domain binding protein 2 antibody, SH3-domain binding protein 2 antibody, SH3BP2 antibody, Sh3bp2 antibody
    Background
    SH3BP2 has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases, and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism.
    Alias Symbols: 3BP2, CRBM, CRPM, FLJ42079, RES4-23, 3BP-2
    Protein Interaction Partner: RNF146, TNKS2, PDLIM7, TNKS, UBC, ERBB2, VAV1, SYK, SRC, CBL, SH3KBP1, DBNL, VAV3, LAT, VAV2, PLCG2, TF, ABL1, ZAP70, PLCG1, LCK, YWHAQ, FYN, FLT3, FGFR1, GRB2,
    Protein Size: 561
    Molecular Weight
    62 kDa
    Gene ID
    6452
    NCBI Accession
    NM_003023, NP_003014
    UniProt
    P78314
    Pathways
    TCR Signaling
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