RPS6KB1 antibody (N-Term)

Catalog No. ABIN2786770

The Rabbit Polyclonal anti-RPS6KB1 antibody (ABIN2786770) specifically detects RPS6KB1 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Rabbit, Dog, Pig, Horse, Goat, Zebrafish (Danio rerio) and Guinea Pig samples.

Quick Overview for RPS6KB1 antibody (N-Term) (ABIN2786770)

Target: RPS6KB1 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1))

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Pig, Horse, Goat, Zebrafish (Danio rerio), Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPS6KB1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RPS6KB1 Antibody

Binding Specificity: N-Term

Sequence: KFEISETSVN RGPEKIRPEC FELLRVLGKG GYGKVFQVRK VTGANTGKIF

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 82%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against RPS6KB1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RPS6KB1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 525 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RPS6KB1

Target: RPS6KB1 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1))

Alternative Name: RPS6KB1

Background: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this prot
Alias Symbols: PS6K, S6K, S6K1, STK14A, p70(S6K)-alpha, p70-S6K, p70-alpha
Protein Interaction Partner: NR1I2, EIF3B, RHEB, NCBP1, MTOR, EIF4E, HTT, UBC, MAPK8, tor1, TRIB2, EIF3F, STAT1, URI1, RPTOR, KIR3DL1, HSP90AA1, MAPT, APP, PLD2, IRS1, MAPKAP1, MLST8, RPS6, SQSTM1, EIF3H, NFATC1, tor2, ELAVL1, NEDD4, MXD1, DPPA4, CLEC3B, MDM2, EP300, KAT2B, POLDIP3,
Protein Size: 525

Molecular Weight: 59 kDa

Gene ID: 6198

NCBI Accession: NM_003161, NP_003152

UniProt: P23443

Pathways: PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Regulation of Cell Size, Skeletal Muscle Fiber Development, Feeding Behaviour, G-protein mediated Events, Smooth Muscle Cell Migration, Interaction of EGFR with phospholipase C-gamma, Warburg Effect