QARS antibody (N-Term)

Catalog No. ABIN2786804

This Rabbit Polyclonal antibody specifically detects QARS in WB. It exhibits reactivity toward Human, Rat, Mouse, Cow, Dog, Horse, Pig, Rabbit, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for QARS antibody (N-Term) (ABIN2786804)

Target: QARS (Glutaminyl-tRNA Synthetase (QARS))

Reactivity: Human, Rat, Mouse, Cow, Dog, Horse, Pig, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This QARS antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-QARS Antibody

Binding Specificity: N-Term

Purpose: QARS Antibody - N-terminal region

Sequence: DQTLSLMEQL RGEALKFHKP GENYKTPGYV VTPHTMNLLK QHLEITGGQV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against QARS. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human QARS

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56628-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for QARS

Target: QARS (Glutaminyl-tRNA Synthetase (QARS))

Alternative Name: QARS

Background:

Background Information: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. In metazoans, 9 aminoacyl-tRNA synthetases specific for glutamine (gln), glutamic acid (glu), and 7 other amino acids are associated within a multienzyme complex. Although present in eukaryotes, glutaminyl-tRNA synthetase (QARS) is absent from many prokaryotes, mitochondria, and chloroplasts, in which Gln-tRNA(Gln) is formed by transamidation of the misacylated Glu-tRNA(Gln). Glutaminyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family.

Gene Name: Glutaminyl-tRNA synthetase

Alternative Symbols: QARS, GLNRS, MSCCA, PRO2195

Protein Name: Glutamine--tRNA ligase

Molecular Weight: 88kDa

Gene ID: 5859

NCBI Accession: NP_005042

UniProt: P47897