Retinoblastoma Binding Protein 4 antibody (N-Term)

Catalog No. ABIN2786817

The Rabbit Polyclonal anti-Retinoblastoma Binding Protein 4 antibody has been validated for WB. It is suitable to detect Retinoblastoma Binding Protein 4 in samples from Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Guinea Pig, Horse, Rabbit and Dog.

Quick Overview for Retinoblastoma Binding Protein 4 antibody (N-Term) (ABIN2786817)

Target: Retinoblastoma Binding Protein 4 (RBBP4)

Reactivity: Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Guinea Pig, Horse, Rabbit, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Retinoblastoma Binding Protein 4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Retinoblastoma Binding Protein 4 Antibody

Binding Specificity: N-Term

Sequence: HTSDEQNHLV IASVQLPNDD AQFDASHYDS EKGEFGGFGS VSGKIEIEIK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against RBBP4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RBBP4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 425 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Retinoblastoma Binding Protein 4

Target: Retinoblastoma Binding Protein 4 (RBBP4)

Alternative Name: RBBP4

Background: This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which
Alias Symbols: NURF55, RBAP48
Protein Interaction Partner: HUWE1, MTA1, FUS, HAT1, UBC, HIST1H4A, CEP76, TP53, TUBGCP3, CEP250, DNMT3B, NACC2, MDM2, RNF2, SUZ12, EZH2, RBBP7, PDIA3, DDX39B, ATP6V1A, MTPN, MIB1, FBXO6, CDK20, DYRK4, HIPK4, CHAF1A, UBD, SOX2, NPM1, IGSF8, HDAC1, CD81, PAN2, TSSK3, MTA3, SIN3A, CDYL
Protein Size: 425

Molecular Weight: 48 kDa

Gene ID: 5928

NCBI Accession: NM_005610, NP_005601

UniProt: Q09028

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases, Stem Cell Maintenance, Chromatin Binding, Protein targeting to Nucleus